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Inventor Recognition Program

The UC Santa Cruz Office of Research has created the Inventor Recognition Program (IRP) to acknowledge researchers on a quarterly basis for their U.S. patent awards and to showcase the groundbreaking research that is conducted on the UCSC campus every day. Launched in December 2016, the IRP is meant to recognize the hard work of UCSC faculty, students, and staff and to help them realize the value of their inventions by commercializing their inventions and discoveries.

July to September 2020 IRP Award Winners

METHODS FOR DETERMINING BASE LOCATIONS IN A POLYNUCLEOTIDE

Patent Numbers: US 10,760,117

Current UCSC Inventors:
Miten Jain, Assistant Research Scientist - Biomolecular Engineering
Hugh Olsen, Project Scientist - Biomolecular Engineering
Mark Akeson, Professor - Biomolecular Science & Engineering

This patent describes a method of detecting modified cytosine residues in genomic DNA using nanopore sequencing. In particular, the method detects 5-methylcytosines, 5-hydroxymethyl cytosines, 5-formylcytosines, and 5-carboxylcytosines and involves treating the DNA with a deaminase and a glycosylase. These create an abasic site in the DNA which can be readily detected using nanopore sequencing.

Miten Jain on a motorcycle Hugh Olsen Mark Akeson

SYSTEM FOR CONTINUOUS MUTAGENESIS IN VIVO TO FACILITATE DIRECTED EVOLUTION

Patent Numbers: US 10,760,071

Manel Camps

Current UCSC Inventor:

Manel Camps, Associate Professor - Microbiology & Environmental Toxicology

This patent describes a system of performing in vivo mutagenesis in a continuous culture without selection of mutants resulting in more efficient directed evolution. In particular the patent describes a an error prone DNA polymerase with particular mutations and a method of using it to perform directed evolution in E. coli cells. The method involves coexpressing the mutant polymerase with a gene that is the target of the directed evolution in E. coli. DNA plasmids including the mutation can readily be purified from E. coli and tested on selective media.

Honorary Mentions

Patent(s) Issued as Continuation of Patent Previously Recognized

BAMBAM: PARALLEL COMPARATIVE ANALYSIS OF HIGH-THROUGHPUT SEQUENCING DATA

Patent Numbers: US 10,706,956; US 10,726,945

UCSC Inventor: David Haussler

Inventor previously at UCSC: John Sanborn

PATHWAY RECOGNITION ALGORITHM USING DATA INTEGRATION ON GENOMIC MODELS (PARADIGM)

Patent Numbers: US 10,770,169

UCSC Inventors: David Haussler; Josh Stuart

Inventors previously at UCSC: Charles Vaske; Stephen Benz

4-((2-HYDROXY-3-METHOXYBENZYL)AMINO)BENZENESULFONAMIDE DERIVATIVES AS POTENT AND SELECTIVE INHIBITORS OF 12-LIPOXYGENASE

Patent Numbers: US 10,752,581

UCSC Inventor: Ted Holman

See all IRP award winners

The IRP is managed by Jeff Jackson, Director of Intellectual Property Management in the office of Industry Alliances and Technology Commercialization (IATC).

For more information about the IRP, the honorees, their patents, other campus inventions and discoveries, or IP portfolio management services, please contact the IATC.

Would you like to be an IRP award winner?

If you are doing research and you invent something new and useful, that other people need, you likely can be an IRP award winner. Start by using UCSC IATC's new Invention Disclosure Form (described here). Once you have submitted that, IATC's IP Management team will work with you to determine if your invention is suitable for protection with a patent. Inventors who have patents issue receive the award at the time the patent grants.

Check out the list of technologies available from the University of California.

University of California, Santa Cruz
Industry Alliances & Technology Commercialization
Kerr Hall — Room 413
Santa Cruz, CA 95064
Tel: 831.459.5415
innovation@ucsc.edu