IRB Initial Submission

• Complete your Initial Submission as early as possible.
• Be prepared to spend some time creating your submission.
• Provide information with a high level of detail, to provide clear information to reviewers to ensure compliance.
• Confirm you can log in to Cayuse Human Ethics.
• Learn about who can be principal investigator (PI).
• Learn about who should be included as an investigator.
• If you are a student, your faculty sponsor should be listed as PI and will certify the submission, and you should be listed as co-Principal Investigator (co-PI).
• A determination cannot be made until all study team members have met their training requirements.
• Attachments are not required for studies that fall into one or more exempt categories.
• For studies that do not qualify for exempt review, prepare required attachments using available forms and templates.
• Although general templates are not available, prepare additional required attachments when appropriate (e.g., questions, debriefing materials, and community resources).
• Use language that could be understood by a layperson. Avoid jargon, and when unavoidable, provide explanations.
• Be sure descriptions are consistent with the information provided in any related grant or contract applications.

• Log in to Cayuse Human Ethics.
• Select the “+ New Study” button.
• Enter the study title and select the check mark button.
• Select the “+ New Submission” button.
• Select the type “Initial.”
• Select the “Complete Submission” link and follow the instructions to fill out the submission.
• When the submission is complete, follow the instructions for submitting.
• The PI and the co-PI (if applicable) will be sent emails with instructions for certifying the submission in Cayuse. 
• Once all certifications are entered, the submission will be routed to ORCA for review and the PI, co-PI (if applicable), and primary contact will receive an acknowledgment email.
  

When an initial submission is created but a review is not completed, a study may be withdrawn. Once a withdrawal has been requested, the only way to proceed with review is to create a new study and new initial submission in Cayuse Human Ethics.