Cayuse Human Ethics is a web-based protocol management system that is used by investigators, ORCA staff, and IRB committee members. Investigators use it to prepare, submit, and route all initial human subjects research studies, as well as make modifications, request renewals, and report incidents.
More about Cayuse at UC Santa Cruz
Log in to Cayuse Human Ethics
To access Cayuse Human Ethics, go to https://ucsc.cayuse424.com/rs/irb/ and enter your CruzID and Gold password.
If you get a blank page upon log in, refresh your browser tab. If this does not resolve the issue, try logging into the Cayuse Research Suite at https://ucsc.cayuse424.com/ and selecting the link Cayuse IRB (Human Studies Compliance).
If you try to log in and get an error message, request a Cayuse account.
If these do not resolve your issue, email orca@ucsc.edu for assistance.
Create a Cayuse account
Each UC Santa Cruz study team member will need a Cayuse account before they can be added to a study submission. To create a Cayuse account, fill out and submit the Cayuse Request form using the option “Create User Account.”
Study team member information
Some places in Cayuse Human Ethics (like the “Research Personnel” section) display information about people. If the name, phone, or organization (department or unit) shown for a person needs updating, use the Cayuse Request form and choose option “Update User Information.”
- Name used is the person’s lived name. Instructions for changing lived name
- Email address in Cayuse needs to be the person’s assigned CruzID@ucsc.edu, not an email alias. If a different email address than expected is shown for a person, confirm their assigned CruzID before submitting a request to update information.
- Address is always the main UC Santa Cruz campus address.
When to use Cayuse Human Ethics
Request a review of a study: IRB Initial Submission
IRB review and approval process
Make changes to an approved study: IRB Modification Submission
Continuing review and administrative check-in: IRB Renewal Submission
Close out a study: IRB Closure Submission
Cayuse Human Ethics Guide for Researchers
- Researcher Dashboard Overview Video
- Creating a New Study
- Creating an Initial Submission
- Completing Submission Forms
- Completing a Submission
- Searching for Studies and Submissions
- Viewing and Downloading Letters
- Addressing Comments
- Viewing Submission Details and History
- Understanding Submission Types
- Creating a Modification Submission
- Creating a Renewal Submission
- Closing a Study
- Deleting a Study or Submission
- Working with Legacy Submissions
Credit: Cayuse
Help with Cayuse Human Ethics
Resource Center
Once you’ve logged in to Cayuse Human Ethics, select the orange question mark icon in the bottom right corner of the window to open the Resource Center.
- Select Show Me How To… and choose the action you want to complete, and the system will walk you through it.
- Select Help Center to see suggested articles, or search for a support article.
ORCA assistance
For help with quick questions or issues, email orca@ucsc.edu.
For individualized help with working through a submission, complex questions, or for an individual Cayuse Human Ethics training session, sign up for a support appointment.
If the available times don’t work for you, email orca@ucsc.edu to arrange for a different time.